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Overview, Scleroderma (sklair-oh-DUR-muh) is a group of unusual diseases that include the hardening and tightening up of the skin and connective tissues. Scleroderma impacts ladies more frequently than men and most frequently takes place between the ages of 30 and 50. While there is no cure for scleroderma, a range of treatments can ease signs and enhance lifestyle.

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In some people, scleroderma impacts only the skin But in numerous people, scleroderma also damages structures beyond the skin, such as capillary, internal organs and the gastrointestinal system (systemic scleroderma). Symptoms and signs vary, depending on which type of scleroderma you have. Products & Solutions, Program more products from Mayo Center Symptoms, Scleroderma's symptoms and signs vary, depending upon which parts of your body are impacted: Nearly everyone who has scleroderma experiences a hardening and tightening up of spots of skin.
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The number, place and size of the spots differ by kind of scleroderma. Skin can appear glossy since it's so tight, and motion of the afflicted location may be restricted. Among the earliest signs of systemic scleroderma is Raynaud's illness, which causes the small capillary in your fingers and toes to agreement in action to cold temperature levels or emotional distress.

Raynaud's disease likewise occurs in people who don't have scleroderma. Scleroderma can cause a range of digestion symptoms, depending upon which part of the gastrointestinal system is affected. If the esophagus is impacted, you might have heartburn or difficulty swallowing. If the intestinal tracts are affected, you may have cramps, bloating, diarrhea or irregularity.
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Scleroderma can affect the function of the heart, lungs or kidneys to differing degrees. Also Found Here , if left neglected, can become lethal. Causes, Scleroderma results from an overproduction and build-up of collagen in body tissues. Collagen is a fibrous type of protein that makes up your body's connective tissues, including your skin.
Probably, scleroderma is brought on by a combination of elements, consisting of immune system issues, genes and environmental triggers. Risk aspects, Anyone can get scleroderma, however it does occur far more often in ladies than in guys. A number of combined aspects appear to affect the danger of developing scleroderma: People who have specific gene variations appear to be most likely to establish scleroderma.